Default mode network analysis associated with memory impairment in acute mild traumatic brain injury
10.3969/j.issn.1006-5725.2024.10.014
- VernacularTitle:急性轻度创伤性脑损伤与记忆障碍相关默认模式网络分析
- Author:
Zhe ZENG
1
;
Lin LUO
;
Qiang CHEN
;
Siqi HOU
;
Shengzhe JIANG
Author Information
1. 内蒙古科技大学包头医学院第一附属医院医学影像科(内蒙古包头 014010)
- Keywords:
mild traumatic brain injury;
resting-state functional MRI;
functional Magnetic Resonance Imaging;
dysmnesia;
functional connection
- From:
The Journal of Practical Medicine
2024;40(10):1412-1417
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes of memory function in patients with mild traumatic brain injury(mTBI),and to explore the correlation between functional connection(FC)changes and montreal cognitive assessment(MoCA)scale scores in the mTBI cohort.Methods Thirty-nine patients with acute mTBI and 39 healthy controls were prospectively collected.All subjects underwent rs-fMRI scans,and FC values were calculated in both groups.Results Compared with healthy controls,the FC of the left posterior cingulate cortex,the left cuneus and the right calcarine fissure were enhanced.The FC of the left orbital superior frontal gyrus with the right superior temporal gyrus and the right postcentral gyrus was enhanced,and the FC of the right parahippocampal gyrus with the right medial and lateral cingulate gyrus,right thalamus and right caudate nucleus was weakened.Correlation analysis showed that there was no significant correlation between MoCA scale score and FC based on DMN network nodes.Conclusion The DMN network was damaged in patients with acute mTBI,and the memory function was impaired.In addition,no correlation was found between FC abnormalities and MoCA scale scores in this study
