Research progress on the relationship between non-coding RNA and liver regeneration
10.3760/cma.j.cn501113-20190924-00352
- VernacularTitle:非编码RNA与肝再生关系的研究进展
- Author:
Guantong LI
1
;
Tao HAN
;
Yu ZHANG
;
Shuai SHAO
Author Information
1. 天津医科大学三中心临床学院 300170
- Keywords:
Long non-coding RNA (lncRNA);
Liver regeneration;
miRNA
- From:
Chinese Journal of Hepatology
2021;29(5):480-483
- CountryChina
- Language:Chinese
-
Abstract:
After partial hepatectomy (PH) or liver injury, hepatocytes in a proliferating quiescent state are activated and begin to expand to repair the damaged liver. In recent years, studies have recognized that non-coding RNA (ncRNA) represented by microRNA (miRNA) and long non-coding RNA (lncRNA) can participate in liver regeneration by regulating the proliferation, apoptosis, autophagy, and proliferation and migration of hepatic progenitor cells (HPCs). This article reviews the relationship between miRNA, lncRNA, and liver regeneration, with a view to provide a new therapeutic strategies for liver disease and liver regeneration.
