Sarcopenia associated with chronic obstructive pulmonary disease
10.3969/j.issn.1006-5725.2024.09.001
- VernacularTitle:慢性阻塞性肺疾病合并肌少症的研究进展
- Author:
Shifang YANG
1
;
Xinglin GAO
;
Jing LI
;
Lupeng JI
Author Information
1. 南方医科大学附属广东省人民医院(广东省医学科学院)呼吸与危重症医学科(广州 510080)
- Keywords:
chronic obstructive pulmonary disease;
sarcopenia;
progress
- From:
The Journal of Practical Medicine
2024;40(9):1181-1185
- CountryChina
- Language:Chinese
-
Abstract:
Sarcopenia is a progressive and systemic skeletal muscle disease and an important extrapulmo-nary complication of chronic obstructive pulmonary disease(COPD).Multiple studies have confirmed that COPD patients with sarcopenia have more severe airflow obstruction and emphysema,higher dyspnea index scores,reduced quality of life and exercise capacity,frequent acute exacerbations,and increased mortality.Although sarcopenia has been mentioned as a complication of COPD for many years,current clinical practice has received insufficient attention and insufficient intervention.The main reason is that its pathogenesis is unknown and drug treatment regi-mens are ineffective.As more and more research has been done on COPD combined with sarcopenia in recent years,this article reviews the current research progress to pay attention to further research and early intervention,including new mechanisms,diagnostic criteria,and drug treatment progress.
