Analysis of hospital-acquired infection pathogens and antibiotic resistance in neurosurgery inpatients
10.16753/j.cnki.1008-2344.2024.05.008
- VernacularTitle:神经外科住院患者医院感染病原菌与耐药性分析
- Author:
Jilin LI
1
;
Hua CHEN
;
Quan ZHANG
;
Xianglu LIU
Author Information
1. 复旦大学附属中山医院青浦分院神经外科,上海 201700
- Keywords:
neurosurgery;
inpatients;
hospital-acquired infection;
pathogenic bacteria;
drug resistance
- From:
Journal of Shenyang Medical College
2024;26(5):485-489
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively analyze the distribution and changes in common pathogenic bacteria isolated from inpatients in department of neurosurgery and their resistance,so as to provide a basis for the rational use of antimicrobial drugs and the control of pathogen resistance rates.Methods:The results of 7 636 specimens from neurosurgery inpatients admitted to the hospital between Jul 1,2020,and Jul 1,2023 were collected and analyzed.The distribution and resistance rates of infecting pathogens were analyzed as well.Results:Out of 7 636 specimens,3 205 strains of pathogenic bacteria were isolated.Sputum specimens were the most common,totaling 2 790 strains,accounting for 87.05%of all.Gram-negative bacteria were the predominant isolates,with 2 586 strains,accounting for 80.69%.The resistance rates of both Gram-negative and Gram-positive bacteria showed an increasing trend,while the resistance rate of fungi showed a decreasing trend.Gram-positive bacteria remained highly sensitive to vancomycin and linezolid.Conclusion:Among the cultured specimens obtained from inpatients in neurosurgery,Gram-negative bacteria are the predominant isolates,and there is an overall increasing trend in the resistance rates of the pathogens over the years.
