Research progress of autoantibodies in primary biliary cholangitis
10.3760/cma.j.cn501113-20190323-00093
- VernacularTitle:原发性胆汁性胆管炎自身抗体的研究进展
- Author:
Yaxing SHI
1
;
Zongji ZHANG
;
Lijuan SHEN
Author Information
1. 昆明医科大学基础医学院病理学与病理生理学系 650500
- Keywords:
Primary biliary cholangitis;
Auto-antibodies;
Research progress
- From:
Chinese Journal of Hepatology
2021;29(2):175-178
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is a chronic, progressive, intrahepatic cholestasis disease. Its occurrence and development are accompanied by changes in the titer of autoantibodies. However, its pathogenesis, extent of autoantibody changes and their effects are not yet fully understood. Therefore, there is a lack of effective methods for early diagnosis of PBC in patients. Finding specific PBC autoantibody markers will greatly improve the diagnostic efficiency and save early treatment time, thereby improving therapeutic effect and prognosis. This article summarizes several PBC-related serum autoantibody markers.
