Study of portal venous pressure gradient to predict high-hepatic encephalopathy-risk population post TIPS

VernacularTitle:门静脉压力梯度预测TIPS术后高危人群肝性脑病的研究
Author: Hao ZHANG ¹ ; Jiajia PAN ; Xiaofen JIANG ; Jiejun LIN ; Lijie LU ; Jianguo CHU
Author Information

1. 温州市中心医院消化内科　325000
Keywords: Hepatic encephalopathy; Transjugular intrahepatic portosystemic shunt; Portosystemic gradient
From: Chinese Journal of Hepatology 2021;29(1):72-74
CountryChina
Language:Chinese
Abstract: Transjugular intrahepatic portosystemic shunt (TIPS) can effectively reduce the portal venous pressure and relieve the clinical complications related to portal hypertension. However, hepatic encephalopathy (HE) is still the main complication post TIPS. Studies have shown that patients over 65 years old with liver function reserve in Child-Pugh grade C are the high-HE-risk group post TIPS, and early TIPS treatment can benefit the survival of these high-risk patients. In this study, TIPS was used to treat 60 cases aged > 65 years old and liver function reserve in Child-Pugh grade C (decompensated liver cirrhosis) with esophagogastric variceal bleeding. The clinical results of 1-year was observed and the porto systemic gradient (PSG) was evaluated. The relationship between the incidence of HE and the PSG of patients with and without HE were compared to evaluate the effect of PSG on the incidence of HE.