Effect of resina draconis for external application on pressure ulcers:a Meta-analysis
10.3760/cma.j.issn.1674-2907.2017.23.017
- VernacularTitle:龙血竭胶囊粉外敷治疗压疮疗效的Meta分析
- Author:
Shuangtai LIU
1
;
Xiaoyan CHEN
;
Hong WENG
;
Ting WANG
;
Shanzhen YU
;
Cui LUO
;
Li YE
Author Information
1. 武汉大学中南医院泌尿外科
- Keywords:
Pressure ulcers;
Resina draconis;
Randomized controlled trial;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2017;23(23):3016-3024
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically review the efficacy and safety of resina draconis capsule in the treatment of pressure ulcers.Methods We searched the PubMed,Embase,The Cochrane Library,CBM, CNKI,VIP,and WanFang Data from their inception to August 2016. Two reviewers independently screened literature,extracted data and assessed the risk of bias of included studies. The meta-analysis was performed by using RevMan 5.3 software.Results A total of 36 RCTs involving 1902 patients were included. The results of meta-analysis showed that:as for the total effective rate,resina draconis capsule was superior to conventional disinfectant/preservative [RR=1.24, 95%CI(1.15,1.34),P<0.00001] and antibiotics [RR=1.17,95%CI (1.09,1.26),P<0.0001],and there was no significant difference with Shirun Shaoshang cream [RR=1.36, 95%CI(0.88,2.11),P=0.17]. In terms of recovery rate,resina draconis capsule was superior to conventional disinfectant/preservative [RR=1.87,95%CI(1.41,2.49),P<0.00001] and antibiotics [RR=2.11,95%CI (1.77,2.51),P<0.00001],and there was no significant difference with Shirun Shaoshang cream [RR=1.54, 95%CI (1.00,2.38),P=0.05]. As regard to the wound healing time,resina draconis capsule was superior to conventional disinfectant/preservative [MD=-10.50,95%CI(-15.52,-5.48),P<0.0001],antibiotics [MD=-8.59,95%CI(-11.45,-5.73),P<0.00001],and Shirun Shaoshang cream [MD=-7.00,95%CI (-8.34,-5.66),P<0.00001]. No obvious event of adverse effect was reported.Conclusions According to the current evidence,the efficacy of resina draconis capsule is superior to conventional disinfectant/preservative, antibiotics,and Shirun Shaoshang cream in treatment of pressure ulcers.
