Roles of periodontal pathogens in the adverse pregnancy
10.3969/j.issn.1001-3733.2024.06.019
- VernacularTitle:牙周致病菌在不良妊娠发生发展中的作用研究
- Author:
Zihui HE
1
;
Xinna BAI
;
Binjie LIU
;
Zhao YU
;
Qian TANG
;
Hao PAN
Author Information
1. 410008 长沙,湖南中南大学湘雅口腔医院·中南大学湘雅口腔医学院·口腔健康研究湖南省重点实验室牙周科
- Keywords:
Periodontitis;
Adverse pregnancy;
Periodontal pathogens;
Intrauterine infection
- From:
Journal of Practical Stomatology
2024;40(6):849-854
- CountryChina
- Language:Chinese
-
Abstract:
Periodontitis is closely related to systemic health,especially adverse pregnancy.Periodontal pathogens are actively in-volved in the formation and development of intrauterine infections.Studies have shown that infection by periodontal pathogens is an im-portant risk factor for adverse pregnancy.Periodontal pathogens reach the uterus via the hematogenous or retrograde route,and the bacte-ria,their virulence factors,and the immunoinflammatory mediators produced by the pathogens promote each other and together mediate the development of intrauterine infections and ultimately lead to adverse pregnancies.This article reviews the role of periodontitis and perio-dontal pathogens in adverse pregnancies and their mechanisms of infection to provide new possibilities for improving the birth rate.
