The impact of metformin on marginal bone loss at the edge of implants in patients with type 2 diabetes mel-litus and exercise habit
10.3969/j.issn.1001-3733.2024.06.007
- VernacularTitle:二甲双胍对有运动习惯的T2DM患者种植体边缘骨吸收的影响
- Author:
Huan TIAN
1
;
Zhiwen SHAO
;
Guoqiang ZHAO
;
Zian YI
;
Zijun CHEN
;
Yuxi WANG
;
Banglian DENG
;
Yingliang SONG
;
Xiangdong LIU
Author Information
1. 710032 西安,口颌系统重建与再生全国重点实验室,国家口腔疾病临床医学研究中心,陕西省口腔生物工程技术研究中心,空军军医大学第三附属医院口腔种植科
- Keywords:
Implant restoration;
Type 2 diabetes mellitus;
Metformin;
Exercise hab-it;
Marginal bone loss
- From:
Journal of Practical Stomatology
2024;40(6):775-782
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effects of metformin on marginal bone resorption of implants in patients with type 2 diabetes melli-tus(T2DM)and exercise habit.Methods:63 cases with 73 implants were included.Among them,there were 41 cases(47 implants)without T2DM in group N,10 cases(13 implants)with T2DM and without exercise habit in group M,12 cases(12 implants)with T2DM and exercise habit in the MR group.The patients were followed up at 6 months,1 and 2 years after implantation.The marginal bone loss(MBL).Implantation success rate and peri-implantitis incidence rate were compared among the groups.Results:The bone resorption of the proximal and median margins of the long-term bone level of the implants in the N and MR groups were significantly lower than that in the M group(P=0.001 and P=0.000 5,respectively).The implant success rates of group N,MR and M were 95.74％,100％and 76.92％,respectively.The incidence of peri-implantitis of the three groups was 2.13％,0 and 15.38％,respec-tively.Conclusion:Metformin is more effective in the improvement of the long-term marginal bone resorption of implants,increase the success rate of implants,and reduce the incidence of peri-implantitis in patients with T2DM and exercise habit in the mandibular first molar area.
