The impacts of periodontal-orthodontic treatment on periodontal indicators,bone metabolism and serum sICAM-1 and MCP-1 levels in patients with anterior tooth displacement(ATD)caused by periodontitis
10.3969/j.issn.1001-3733.2024.05.013
- VernacularTitle:牙周-正畸治疗对牙周炎致前牙移位患者牙周指标、骨代谢及血清sICAM-1、MCP-1水平的影响
- Author:
Chenyu CAI
1
;
Yuanyuan LI
;
Suna LI
Author Information
1. 053000,衡水市人民医院口腔正畸修复科
- Keywords:
Periodontal splints;
Orthodontics;
Periodontitis;
Anterior tooth displacement;
Bone metabolism;
Pe-riodontitis
- From:
Journal of Practical Stomatology
2024;40(5):678-682
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the impacts of periodontal-orthodontic treatment on periodontal indicators,bone metabolism and serum levels of soluble intercellular adhesion molecule-1(sICAM-1)and monocyte chemotactic protein-1(MCP-1)in patients with an-terior tooth displacement(ATD)caused by periodontitis.Methods:60 patients with ATD caused by periodontitis were included and randomly divided into a reference group(n=30,periodontal basic treatment+periodontal splint treatment)and a study group(n=30,combination of orthodontic treatment with the reference treatment).31 ATD patients who only received periodontal basic treatment were included into the blank control group.The probing depth(PD),plaque index(PLI)and gingival index(GI),tooth looseness,bone me-tabolism indicators osteocalcin(OCN)and osteoprotegerin(OPG),and serum inflammatory indicators(sICAM-1 and MCP-1)were compared among the 3 groups before and after treatment.Results:After 6 months of treatment,the levels of PD,PLI,GI,and serum sICAM-1 and MCP-1 in the 3 groups were lower than those before treatment(P＜0.05),and lower in the study group than in the refer-ence group and blank control group(P＜0.05);the looseness of the affected teeth in the 3 groups was decreased(P＜0.05),and in the study group was less than in the reference group and blank control group(P＜0.05);the levels of OCN and OPG in the 3 groups were higher(P＜0.05)than those before treatment,and in the study group were higher than in the reference group and blank control group(P＜0.05).Conclusion:Periodontal-orthodontic treatment can obviously reduce the levels of inflammatory factors in serum,effectively regulate bone metabolism and improve periodontal health in patients with ATD caused by periodontitis.
