Prevention and treatment effect of baxianxiaoyao decoction medicated bathing on rat pressure injury
10.3760/cma.j.issn.1674-2907.2017.21.004
- VernacularTitle:八仙逍遥汤药浴对大鼠压力性损伤的预防和治疗效果
- Author:
Shuwen CHANG
1
,
2
;
Daiji MIURA
;
Akio KITAYAMA
;
Honoka ISSHI
;
Jingyan LIANG
;
Qihong CHEN
;
Yusheng SHU
;
En TAKASHI
Author Information
1. 225001 扬州大学护理学院
2. 225001扬州,江苏省苏北人民医院ICU
- Keywords:
Drugs;
Chinese herbal;
Rats;
Pressure injury;
Baths therapy;
Baxianxiaoyao decoction
- From:
Chinese Journal of Modern Nursing
2017;23(21):2714-2720
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the preventive and therapeutic effects of Baxianxiaoyao decoction medicated bath on pressure injury wound in rats.Methods The research was started from April 2016 to February 2017. The experiment was approved by the animal experimental ethics committee and was finished in the basic medical laboratory of Nagano University of Nursing in Japan. A total of 24 rats were divided into 3 groups averagely,and there were the control group(group A),the tap-water bath group(group B) and the traditional Chinese medicine bath group(group C). Group B rats used tap-water bath,and group C rats used traditional Chinese medicine bath,while the rats in group A did not bath. After bathing for 2 weeks,the pressure injury model was made on the rats' skin,and then the average of ulcer area and the maximum- minimum concentration difference were calculated by Image-J ;besides the healing rate,wound center temperature,skin moisture were compared among the three groups.Results For the 12 h pressure injury area after three groups rats model established,the group A was(137.060±18.258) mm2,Group B(123.310±14.969) mm2,group C (92.520±11.159) mm2(F=73.235,P<0.05);Image-J measures the average area of pressure injury picture among three groups and maximum-minimum concentration difference of picture(F=8.13,4.91;P<0.01).The rate of wound healing was statistically difference after the PI model at 12 hours,4 days,8 days,12 days (F=8.058, 12.024,17.360,26.006;P<0.05);however,the skin moisture had no statistical significance (P>0.05). Conclusions Baxianxiaoyao Decoction medicated bath is an effective way to prevent and treat pressure injury wound,and it can promote wound healing.
