A case of levofloxacin-induced anaphylactic shock in a patient with oral and maxillofacial space infection

VernacularTitle:左氧氟沙星治疗口腔颌面部间隙感染致过敏性休克1例
Author: Zhigang GUO ¹ ; Xiumei FANG ; Jiansen YANG ; Tianqi JIA ; Liguang ZHENG
Author Information

1. 100081,北京大学口腔医学院·口腔医院药剂科,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心
Keywords: Levofloxacin; Anaphylactic shock; Oral and maxillofacial space infection; Adverse drug reaction
From: Journal of Practical Stomatology 2024;40(4):584-586
CountryChina
Language:Chinese
Abstract: Oral and maxillofacial space infection(OMSI)as a mostly mixed infection,often requires the combination of anti-aerobe and an-ti-anaerobe antibiotics.The use of third-generation quinolones,such as levofloxacin,is limited in OMSI due to the tendon rupture and other serious adverse drug reactions(ADR).In the treatment of a case with OMSI and anaphilactic shock induced by levofloxacin,the association evaluation method of ADR and literature review method participated by clinical pharmacists were used.Suggestions on rational drug use and ADR treatment were gained,the patient was timely rescued from anaphylactic and cured of OMSI.