Influence of probiotics on gastrointestinal function in critical patients with enteral nutrition: a Meta-analysis
10.3760/cma.j.issn.1674-2907.2017.20.009
- VernacularTitle:益生菌对危重症肠内营养患者胃肠功能影响的Meta分析
- Author:
Li ZHANG
1
;
Ying WANG
;
Peipei LI
;
Ziqiao YU
;
Zhiqiang CHEN
Author Information
1. 300193,天津中医药大学研究生院
- Keywords:
Probiotics;
Enteral nutrition;
Critical illness;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2017;23(20):2609-2614
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically review the effects of probiotics on gastrointestinal function in critical patients with enteral nutrition.Methods We searched Pubmed, EMBASE, Web of Science, Cochrane, CNKI, WanFang Data, VIP and CBM to collect randomized controlled trials (RCTs) about probiotics improve gastrointestinal function and nutritional status in patients with enteral nutrition. Two reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies. Then, Meta-analysis was performed using Rev Man 5.3.Results A total of 11 RCTs involving 1042 patients were included. The results of meta-analysis showed that compared with the placebo/blank group, the probiotics groups had lower incidence rates of diarrhea, ventosity, astriction, emesis, reduce target feeding time, improved Alb levels and Hb levels, while there were no significant differences between two groups in time of nutritional support.Conclusions Current evidence indicates that, compared with enteral nutrition alone, probiotics combined with enteral nutrition can improve patients' gastrointestinal function and Alb,Hb levels, and reduce target feeding time.
