Brief discussion on the taboo and application of stem cell transplantation in the treatment of liver cancer
10.3760/cma.j.cn501113-20200602-00289
- VernacularTitle:干细胞移植在肝癌治疗中的禁忌与应用
- Author:
Yanyu HU
1
;
Peilin ZHANG
Author Information
1. 海军军医大学第三附属医院 国家肝癌科学中心，上海 201805
- Keywords:
Hepatocellular carcinoma;
Stem cell transplantation therapy;
Self-renewal;
Pluripotency
- From:
Chinese Journal of Hepatology
2020;28(6):479-480
- CountryChina
- Language:Chinese
-
Abstract:
Liver cancer is the second-highest mortality cancer in China. It is highly occult, and there is no effective treatment so far. In recent years, stem cell transplantation, especially mesenchymal stem cell (MSCs) transplantation, has been widely used in the treatment of various diseases. Nevertheless, the industry has reached a consensus that malignant tumors are the forbidden area of this transplantation therapy. This is closely related to the two main characteristics of stem cells themselves, namely "self-renewal" and "pluripotency". The following is an overview of the reasons why stem cells, especially MSCs, have become taboo in tumor treatment and their potential application methods, so as to provide some references for further research on this therapy.
