Intranuclear cytoplasmic autophagosomes cause specific nucleolysis and cell death of liver cancer cells and liver cells
10.3760/cma.j.cn501113-20190529-00193
- VernacularTitle:核内胞质性自噬体导致肝癌细胞和肝细胞特殊性核溶解与细胞死亡
- Author:
Ming YE
1
;
Pin TU
;
Guimei LI
;
Ying ZHANG
;
Meizhao LE
Author Information
1. 解放军八一医院病理科,南京 210002
- Keywords:
Carcinoma, hepatocellular;
Hepatocytes;
Specific nucleolysis;
Cell death
- From:
Chinese Journal of Hepatology
2020;28(5):449-451
- CountryChina
- Language:Chinese
-
Abstract:
The structure and performance of nuclear cytoplasmic autophagosomes was explored. Seventeen cases of hepatocellular carcinoma and liver cells with other diseases from liver tissues were selected. The nuclear cytoplasm were isolated and degraded by the nuclear membrane. Damaged cytoplasm had damaged its own membrane and the surrounding nuclear tissues other than the nuclear membrane, leading to specific nucleolysis and cell death of liver cancer cells and liver cells.