Comparison between rapid intravenous drip of Shenfu and pumping of Dopamine in interventional therapy of acute inferior wall myocardial infarction
10.3760/cma.j.issn.1674-2907.2017.18.016
- VernacularTitle:参附快速静脉滴注与多巴胺泵入在急性下壁心肌梗死介入治疗中的应用对比
- Author:
Dongmei ZHANG
1
;
Lihua WANG
;
Dongxiu SUN
;
Changlei SUN
;
Lili DU
;
Kejing YAO
;
Yao LIU
;
Xingcai YU
Author Information
1. 264008,山东省烟台市烟台山医院心导管室
- Keywords:
Dopamine;
Shenfu injection;
Myocardial infarction;
Hypoperfusion;
Percutaneous coronary intervention
- From:
Chinese Journal of Modern Nursing
2017;23(18):2383-2387
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect of pressurized rapid intravenous drip of Shenfu and micro-pumping of dopamine on hypoperfusion in percutaneous coronary intervention (PCI) of acute inferior wall myocardial infarction.Methods A total of 80 patients with acute inferior wall myocardial infarction treated with emergency PCI in Chest Pain Unit of Yantaishan Hospital of Yantai City from May 2014 to May 2015 were enrolled. Then these patients were divided into observation group (n=40,pressurized rapid intravenous drip of normal saline and Shenfu) and control group (n=40,pressurized intravenous drip of normal saline with the same pressure combined with micro-pumping of Dopamine) according to random number table. Blood pressure and heart rate per five minutes were observed and recorded before intravenous drug,five to forty minutes after intravenous drug. Besides,the incidence rates of malignant arrhythmia,vomitting,TIMI grade three flows after intrqvenous drug and major adverse cardiovascular events after 30 days of a follow-up were also observed and recorded.Results Systolic pressure,diastolic pressure and mean arterial pressure of patients between two groups all met and maintained to the expectation after treatment with significant differences between two groups (P<0.05). The incidence rates of malignant arrhythmia,nausea and vomitting in observation group were lower than those in control group with significant differences (P<0.05). There was no statistically significant difference in the proportion of TIMI grade three flows and the incidence of major adverse cardiovascular events after 30 days of a follow-up (P>0.05).Conclusions When the hypoperfusion appears during PCI of acute inferior wall myocardial infarction,the pressurized rapid intravenous drip of Shenfu can improve hypoperfusion which is better than Dopamine in the effects of correcting hypotension and reducing the occurrence of adverse events.
