Influence of comorbidity on frailty in elderly patients with cardiovascular disease and abnormal glucose metabolism: a chain intermediary role of basic activity of daily living and nutritional status
10.3760/cma.j.cn211501-20240126-00232
- VernacularTitle:老年心血管疾病伴糖代谢异常患者共病对衰弱的影响：基本日常生活能力和营养状况的链式中介效应
- Author:
Ying XIN
1
;
Yuping HAN
;
Xiaoming SANG
;
Na LI
;
Cuicui LI
;
Yun ZHU
Author Information
1. 山东第一医科大学附属省立医院急救中心，济南 250021
- Keywords:
Aged;
Nutritional status;
Cardiovascular disease;
Comorbidity;
Frailty;
Basic activity of daily living;
Abnormal glucose metabolism
- From:
Chinese Journal of Practical Nursing
2024;40(27):2142-2149
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the chain mediating effect of basic activity of daily living and nutritional status the effects on comorbidity and frailty, so as to provide guidance for preventing and delaying the frailty of elderly patients with cardiovascular disease and abnormal glucose metabolism.Methods:The cross-sectional study method was adopted, 300 elderly patients with cardiovascular disease and abnormal glucose metabolism who were hospitalized in the cardiovascular medicine ward of Shandong Provincial Hospital Affiliated to Shandong First Medical University, were selected as the study objects from January to August 2022, and were surveyed using General Information Questionnaire, Frailty Scale, Charlson Comorbidity Index Scale, Barthel Index Rating Scale and Mini Nutritional Assessment-Short Form were used to investigate them.Results:A total of 300 questionnaires were collected and 291 valid questionnaires were returned. Out of 291 patients, 167 were male and 124 were female, with an age of (69.55 ± 7.01) years. Comorbidities in elderly patients with cardiovascular disease and abnormal glucose metabolism were positively correlated with frailty ( r=0.414, P<0.01), and negatively correlated with basic activity of daily living and nutritional status ( r=-0.399, -0.373, both P<0.01). Basic activity of daily living was positively correlated with nutritional status ( r=0.575, P<0.01) and negatively correlated with frailty ( r=-0.825, P<0.01). Nutritional status was negatively correlated with frailty ( r=-0.695, P<0.01). The chain mediating model showed that comorbidities had a significant direct effect on frailty (effect value of 0.102), basic activity of daily living partially mediated between comorbidity and frailty (effect value of 0.125). Basic activity of daily living and nutritional status partially chained between comorbidity and frailty (effect value of 0.036). Conclusions:The chain mediating roles of basic activity of daily living and nutritional status between comorbidity and frailty was established. Healthcare professionals should pay attention to the improvement of basic activity of daily living in elderly patients with cardiovascular diseases and abnormal glucose metabolism, guide them to have a reasonable diet to achieve balanced nutrition, and delay the onset and development of frailties.
