Effects of different feeding methods on Ghrelin and growth and development of premature infants
10.3760/cma.j.issn.1674-2907.2017.16.011
- VernacularTitle:不同喂养方式对早产儿生长发育及Ghrelin的影响
- Author:
Xihua HUANG
1
;
Huiyi LI
;
Xueting ZHAO
;
Daiju HU
;
Shuxiang ZHENG
;
Yu WANG
;
Chuming YOU
Author Information
1. 广东省第二人民医院儿科
- Keywords:
Very low birth weight premature infants;
Tube feeding;
Non-nutritive sucking;
Touch
- From:
Chinese Journal of Modern Nursing
2017;23(16):2125-2129
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo compare the effects of different feeding methods on plasma Ghrelin(a peptide hormone)level, growth and development of premature infants.Methods A total of 147 cases of very low birth weight newborn were randomly divided into nasogastric tube feeding group(group A, 38 cases), nasogastric tube feeding combined with non-nutritional sucking group(group B, 39 cases), nasogastric tube feeding combined with infantile touching group(group C,34 cases), nasogastric tube feeding combined with non-nutritional sucking and infantile touching group(group D,36 cases). Anthropometric indicators and plasma Ghrelin levels of premature infants before and after the feeding were compared among four groups.Results At 2 weeks post admission, the body weight of premature infants in four groups were(1503±206)g(group A),(1487±211)g(group B), (1494±228)g(group C), and(1615±242)g(group D). The differences between group D and other groups were statistically significant(t=2.004, 2.262, 2.061;P<0.05). At 4 weeks post admission, the plasma Ghrelin levels of premature infants in four groups were(38.3±7.4)μg/L(group A),(39.3±6.9)μg/L(group B),(35.7±6.6)μg/L(group C), and(34.5±9.1)μg/L(group D). The increases of plasma Ghrelin levels between group A and group C or D were statistically significant(t=2.65,5.20;P<0.05). Similar results were also observed between group B and group C or D(t=3.01, 5.79;P<0.05).Conclusions Nasogastric tube feeding combined with non-nutritional sucking and infantile touching is efficient in improving quality of life of very low birth weight newborns and saving medical cost.