Fstrogen and its receptors in hepatitis B virus-related hepatocellular carcinoma
10.3760/cma.j.issn.1007-3418.2019.03.014
- VernacularTitle:雌激素及其受体与乙型肝炎病毒相关肝癌
- Author:
Shitian YANG
1
;
Juqiang HAN
;
Yadong WANG
;
Chuan SHEN
;
Caiyan ZHAO
Author Information
1. 河北医科大学第三医院感染科
- Keywords:
Hepatitis B;
Hepatocellular carcinoma;
Estrogen
- From:
Chinese Journal of Hepatology
2019;27(3):232-235
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus (-HBV) infection is the most common cause ofhepatocellular carcinoma in China.Epidemiological surveys show that male have a much higher incidence of hepatocellular carcinoma than female.Studies have shown that estrogen and its receptors are associated to gender disparity in hepatocellular carcinoma,but the underlying molecular mechanisms has not yet been fully elucidated.This article reviews the possible mechanisms of estrogen and its receptors in the occurrence and progression of hepatitis B virus-related hepatocellular carcinoma.