Effects of Mucopolysaccharide Polysulfate Cream by ultrasound conductance combined with nursing intervention for prevention and cure of hand-foot syndrome
10.3760/cma.j.issn.1674-2907.2017.15.008
- VernacularTitle:多磺酸粘多糖乳膏经超声电导联合护理干预防治手足综合征的有效性研究
- Author:
Meihua ZHONG
1
;
Leilei MU
;
Dongmei LIU
Author Information
1. 广州医科大学附属第一医院胃肠外科
- Keywords:
Nursing;
Hand-foot syndrome;
Mucopolysaccharide Polysulfate Cream;
Ultrasound;
Conductance
- From:
Chinese Journal of Modern Nursing
2017;23(15):1987-1990
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of Mucopolysaccharide Polysulfate Cream by sound conductance for prevention and cure of hand-foot syndrome (HFS) caused by oral chemotherapy in tumor patients and nursing interventions.Methods A total of 76 patients with colorectal cancer (stageⅡ/Ⅲ) in the authors′ hospital who were taking capecitabine in accordance with the requirements of NCCN guideline were selected as subjects from 1 April 2016 to 8 Octobor 2016. The medical records were coded in selected sequential order with the method of randomised controlled clinical trial. All patients (n=76) were randomly divided into control group (n=38, routine nursing care) and observation group (n=38, routine nursing care + intervention imported by Mucopolysaccharide Polysulfate Cream combined with conductivity apparatus) by random number table. The control effect of HFS caused by capecitabine was compared.Results There were 9 patients (23.7%) with HFS after intervention including 6 cases forⅠ, 3 cases forⅡ, 0 forⅢ. There were 17 patients (44.7%) with HFS after intervention including 9 cases forⅠ,7 cases forⅡ, 1 forⅢ. There was a statistically significant difference in HFS between two groups (Z=2.029,P<0.05). The result of symptom quantized integration of HFS (erythema, edema, dryness, desquamation and so on) of 9 patients with HFS in observation group was obviously better than that of 17 patients with HFS in control group with a significant difference (P<0.05). The score of KPS of 9 patients with HFS in observation group was (88.68±6.80) obviously better than that (82.99±9.51) of 17 patients with HFS in control group with a significant difference (t=2.892,P<0.05).Conclusions The prevention and cure intervention imported by Mucopolysaccharide Polysulfate Cream combined with conductivity apparatus along with nursing intervention can obviously lessen the symptoms of HFS of patients with oral chemotherapy and improve the chemotherapy tolerance.
