Research advances in the role of sphingolipids in HCV and HBV life cycles
10.3760/cma.j.issn.1007-3418.2016.12.016
- VernacularTitle:鞘脂在HCV和HBV生命周期中作用的研究进展
- Author:
Jinyan ZHANG
1
;
Zhongping DUAN
;
Jinlan ZHANG
;
Sujun ZHENG
Author Information
1. 100069,首都医科大学附属北京佑安医院人工肝中心
- Keywords:
Hepatitis B virus;
Hepatitis C virus;
Life cycle stages;
Sphingolipids
- From:
Chinese Journal of Hepatology
2016;24(12):945-947
- CountryChina
- Language:Chinese
-
Abstract:
Sphingolipids and their metabolites are not only important structural molecules of the cell membrane,but also involved in all phases of viral life cycle,including cell adhesion,membrane fusion,viral replication,viral assembly,intracellular transport,protein sorting,and exocytosis.In recent years,sphingolipids have become one of the focuses of lipid research.This article reviews the role of sphingolipids in the life cycles of hepatitis C virus and hepatitis B virus with reference to recent research achievements in China and foreign countries.