Role of high risk-human papilloma virus test in the follow-up of patients who underwent conization of the cervix for cervical intraepithelial neoplasia.
- Author:
Jeong Yeol PARK
1
;
Jaeman BAE
;
Myong Cheol LIM
;
So Yi LIM
;
Dong Ock LEE
;
Sokbom KANG
;
Sang Yoon PARK
;
Byung Ho NAM
;
Sang Soo SEO
Author Information
- Publication Type:Original Article
- Keywords: HR-HPV; Conization; CIN; Recurrence
- MeSH: Cervical Intraepithelial Neoplasia; Cervix Uteri; Conization; Female; Follow-Up Studies; Humans; Odds Ratio; Papilloma; Recurrence; Retrospective Studies; Risk Factors; Viruses
- From:Journal of Gynecologic Oncology 2009;20(2):86-90
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To examine whether the presence of high risk-human papilloma virus (HR-HPV) after conization of the cervix was a risk factor for persistence or recurrence of cervical intraepithelial neoplasia (CIN) and whether HR-HPV test could be a guideline for post-therapy surveillance. METHODS: The study retrospectively analyzed data from 243 patients who underwent LLETZ or CKC of the cervix due to CIN. RESULTS: A positive HR-HPV test result which was performed between 3 and 6 months after procedure was a risk factor for persistent or recurrent cytological (p<0.001, odds ratio [OR]=22.51, 95% confidence interval [CI]=9.74-52.02) and pathological (p<0.001, OR=18.28, 95% CI=5.55-60.20) abnormalities. CONCLUSION: HR-HPV positive patients between 3 and 6 months after procedure should undergo frequent and meticulous post-therapy surveillance, while HR-HPV negative patients do not require such high-level surveillance and could undergo routine surveillance.
