Analysis of multi spiral CT manifestations of advanced gastrointestinal signet ring cell carcinoma
10.3969/j.issn.1002-1671.2024.12.013
- VernacularTitle:进展期胃肠印戒细胞癌多层螺旋CT表现分析
- Author:
Xiwei YUAN
1
;
Longyu CHEN
;
Yi QIU
;
Xiaobing ZHONG
Author Information
1. 遵义医科大学第三附属医院 遵义市第一人民医院放射科,贵州 遵义 563002
- Keywords:
gastrointestinal tract;
signet ring cell carcinoma;
computed tomography
- From:
Journal of Practical Radiology
2024;40(12):1994-1997
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the multi spiral computed tomography(MSCT)characteristics and biological behaviors of advanced gastrointestinal signet ring cell carcinoma(SRCC),so as to provide accurate preoperative type,stage and personalized choice of treatment strategy in clinical practice.Methods The clinical manifestations,five tumor markers and MSCT imaging data of 26 cases(group A)with advanced gastrointestinal SRCC confirmed by surgical or endoscopic biopsy and pathological immunohistochemistry were analyzed retrospectively,and 44 cases(group B)of advanced non-signet ring cell carcinoma(NSRCC)during the same period were randomly selected as the control group.The clinical manifestations,five tumor markers and MSCT imaging features of groups A and B were analyzed.Results There were no significant differences in gender,tumor location,tumor thickness(T)and length(L),and five tumor markers between groups A and B(P＞0.05).There were significant differences in age,main symptoma,tumor thickness-to-length ratio(TLR),angle between cancerous edge and normal tissue(CNA)(P＜0.05).However,age of group A and group B[group A≤50 years old(12/26,46％),group B＞50 years old(42/44,95％)],main symptom(x2=19.085,P＜0.05),tumor TLR(Z=-2.044,P＜0.05)and CNA(x2=14.776,P＜0.05)were significantly different(P＜0.05).Conclusion SRCC affects younger patients and is more likely to originate from the middle and lower parts of the stomach and rectum,with lower TLR,obtuse angle of CNA,and"caterpillar-like"characteristics of colorectal SRCC.
