Prognostic study of pericoronary adipose tissue CT attenuation and coronary artery disease reporting and data system for patients with acute chest pain
10.3969/j.issn.1002-1671.2024.12.008
- VernacularTitle:冠状动脉周围脂肪组织CT值和冠状动脉疾病报告和数据系统分级对急性胸痛患者的预后研究
- Author:
Weixin ZHANG
1
;
Yani BAI
Author Information
1. 山阳县中医医院CT室,陕西 商洛 726400
- Keywords:
pericoronary adipose tissue;
coronary artery disease reporting and data system;
major adverse cardiovascular events;
acute chest pain
- From:
Journal of Practical Radiology
2024;40(12):1968-1973
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prognostic value of pericoronary adipose tissue(PCAT)and coronary artery disease reporting and data system(CAD-RADS)for major adverse cardiovascular events(MACE)in patients with acute chest pain.Methods A total of 1 248 patients with acute chest pain referred for coronary computed tomography angiography(CCTA)were retrospectively selected and the occurrence of MACE was followed up.MACE included unstable angina requiring hospitalization,late coronary revascularization,non-fatal myocardial infarction,and all-cause death.Multivariable Cox regression analysis was used to analyze the relationship between patients'clinical characteristics,CAD-RADS,PCAT CT attenuation and MACE.Results Among 1 248 patients,142 patients(11.38％)experienced MACE.Multivariable Cox regression analysis showed that CAD-RADS categories 2-5[hazard ratio(HR)2.715-9.544;P＜0.001]and right coronary artery(RCA)PCAT CT attenuation(HR 1.028;P=0.019)were independent predictors of MACE after adjusting for clinical risk factors.After adding RCA PCAT CT attenuation on the basis of CAD-RADS,the risk stratification ability of patients was improved to a certain extent(overall x2 value:149.4 vs 157.1;P=0.053).Conclusion RCA PACT CT attenuation and CAD-RADS are independent predictors of MACE.However,adding RCA PCAT CT attenuation to CAD-RADS did not increase the prognostic value of MACE in acute chest pain patients.
