Prevalence of hepatitis C in Tianjin, China and related risk factors
10.3760/cma.j.issn.1007-3418.2016.09.003
- VernacularTitle:天津市丙型病毒性肝炎流行现状及危险因素探讨
- Author:
Haiyan HE
1
;
Ying ZHAO
;
Jing CHEN
;
Chao LI
;
Weishen WU
;
Ying ZHANG
Author Information
1. 300011,天津市疾病预防控制中心病毒性肝炎科
- Keywords:
Hepatitis C;
Epidemic trend;
Infection status;
Risk factors
- From:
Chinese Journal of Hepatology
2016;24(9):647-651
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of hepatitis C in Tianjin,China and major risk factors,and to provide a theoretical basis for the development of scientific prevention and control strategies for hepatitis C.Methods The monitoring system of notifiable infectious diseases was used to establish the database of hepatitis C cases reported from 2004 to 2014 in Tianjin.With reference to the results of serological surveillance and special case-control investigation,a statistical analysis was performed to investigate the epidemiological characteristics and prevalence of hepatitis C in Tianjin,as well as related risk factors.Results The report rate of hepatitis C in Tianjin showed a decreasing trend from 2004 to 2014 (x 2 =150.018,P < 0.01).The group aged 60 years had the highest report rate (9.09/100000),and there were significant differences between this group and other groups (x2 =2540.887,P < 0.01).The six urban districts in Tianjin had the highest report rate (6.54/100000),and there were significant differences between this area and other areas.The multivariate logistic regression analysis showed that a history of surgery (x2 =12.57,P < 0.01),blood transfusion and blood products (x2 =36.67,P < 0.01),hemodialysis (x2 =4.62,P < 0.01),and intravenous drug use (x2 =12.92,P < 0.01) were major risk factors for hepatitis C.Conclusion The epidemic situation of hepatitis C in Tianjin tends to decrease in recent years.Although there is no effective vaccine for hepatitis C,it still can be prevented and treated.The most effective interventions for hepatitis C include strengthening health education and raising the awareness rate of hepatitis C in the whole population,as well as early detection,diagnosis,and treatment.