Quantitative assessment of the impact of prolonged sitting on lumbar intervertebral disc degeneration using T1ρ and T2 mapping
10.3969/j.issn.1002-1671.2024.11.023
- VernacularTitle:T1ρ、T2 mapping定量评估长期久坐对腰椎间盘退行性变的影响
- Author:
Qi ZENG
1
;
Lingling SONG
;
Chen LIANG
;
Lisha NIE
;
Weixin HE
;
Ziwei ZHANG
;
He SUI
Author Information
1. 贵州医科大学附属医院放射科,贵州 贵阳 550004
- Keywords:
magnetic resonance imaging;
T1ρ;
T2 mapping;
lumbar intervertebral disc degeneration
- From:
Journal of Practical Radiology
2024;40(11):1857-1861
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impact of prolonged sitting on lumbar disc degeneration using MRI T1ρ and T2 mapping.Methods A total of 25 taxi drivers(prolonged sitting group)and 24 age-matched non-prolonged sitting volunteers(control group)underwent routine lumbar MRI,T1ρ,and T2 mapping.The differences of T1ρ and T2 values for different Pfirrmann grades of anterior annulus fibrosus(AAF),nucleus pulposus(NP),and posterior annulus fibrosus(PAF)were analyzed using Variance analysis,Spearman correlation test,and receiver operating characteristic(ROC)curve was drawn,with independent t-tests was used for between-group com-parisons.Results Statistically significant differences were observed in T1ρ and T2 values for all Pfirrmann Ⅰ-Ⅱ grades NP and Pfirrmann Ⅱ-Ⅳgrades AAF,NP,and PAF in both groups(P＜0.05).Both T1ρ and T2 values were negatively correlated with Pfirrmann grades.The area under the curve(AUC)of T1ρ values for NP at each Pfirrmann grade were 0.928,0.987,and 0.968,respectively,while the AUC of T2 values for NP were 0.777,0.966,and 0.975,respectively.The T1ρ and T2 values of L4/L5 NP and L5/S1 AAF,NP,and PAF were lower in the prolonged sitting group compared to the control group(P＜0.05).Conclusion T1ρ is superior to T2 mapping in detecting lumbar disc degeneration.Prolonged sitting is more likely to cause degeneration of L4/L5 and L5/S1 inter-vertebral discs.
