Quantitative CT features of peritumoral nodules for predicting the risk of thymic epithelial tumors
10.3969/j.issn.1002-1671.2024.11.007
- VernacularTitle:瘤周结节CT定量特征预测胸腺上皮肿瘤危险度
- Author:
Wei GUO
1
;
Qingyuan HE
;
Xiaohua WANG
;
Huishu YUAN
Author Information
1. 北京大学第三医院放射科,北京 100191
- Keywords:
computed tomography;
thymic epithelial tumors;
peritumoral nodule
- From:
Journal of Practical Radiology
2024;40(11):1784-1787
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predicting value of quantitative CT features of peritumoral nodules for the risk of thymic epi-thelial tumors(TETs).Methods A total of 108 patients with TETs confirmed by pathology were analyzed retrospectively.Accord-ing to the WHO classification of thymic tumors,the patients were divided into high-risk group and low-risk group.The quantitative CT features included the long diameter,volume,mass,and distance between peritumoral nodules and main tumor.The values of these features were assessed using the Mann-Whitney U test,and the thresholds were determined using the receiver operating characteristic(ROC)curve.Results Among 108 TETs patients,there were 45 patients with peritumoral nodules on chest CT,including 30 high-risk group and 15 low-risk group,respectively.Interobserver consistencies were well with intraclass correlation coefficient(ICC)between 0.886 and 0.907.The long diameter,volume,and mass of peritumoral nodules were greater in the high-risk group than in the low-risk group(P＜0.05),and there was no significant difference in the distance to the main tumor(P＞0.05).The mass of peritumoral nodules had the best diagnostic performance in predicting TETs risk,and the thresholds was 27.84 mg with the area under the curve(AUC)of 0.889,sensitivity of 83.3％,specificity of 87.5％,and accuracy of 85.3％,respectively.Conclusion The quantitative CT features of peritumoral nodules especially mass can be useful in predicting the risk of TETs.
