Topological properties of resting-state functional brain networks in patient with trigeminal neuralgia
10.3969/j.issn.1002-1671.2024.11.001
- VernacularTitle:三叉神经痛静息态功能脑网络的拓扑属性研究
- Author:
Xue BAI
1
;
Qiong WU
;
Yang GAO
;
He ZHAO
;
Shaoyu WANG
;
Huapeng ZHANG
Author Information
1. 内蒙古医科大学附属医院影像诊断科,内蒙古 呼和浩特 010050
- Keywords:
trigeminal neuralgia;
resting-state functional magnetic resonance imaging;
graph theory analysis
- From:
Journal of Practical Radiology
2024;40(11):1757-1761
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the intrinsic connectivity alterations of brain-wide functional networks in patient with trigeminal neuralgia(TN)via combining resting-state functional magnetic resonance imaging(rs-fMRI)and graph theory methods.Methods A total of 41 patients with TN(TN group)and 41 healthy controls(HC)(HC group)were recruited,and differences in network topologyat-tributes and correlations with clinical variables were analyzed between the two groups.Results Both groups met the σ standard.The global efficiency(Eg)of TN group was lower than that of HC group(P＜0.05),whereas the λ of TN group was higher than that of HC group(P＜0.05).The node efficiency(Ne)of bilateral rectus gyrus and bilateral pallidum of TN group were significantly higher than those of HC group,while the Ne of left supraparietal gyrus,left angular gyrus,left post-central gyrus,bilateral marginal supraparietal gyrus,and left caudate nucleus of TN group were significantly lower than those of HC group(P＜0.05).The local efficiency(Eloc)of the TN group was negatively correlated with the visual analogue scale(VAS)score(P＜0.05),the clustering coefficient(Cp)of the TN group was negatively correlated with the short-form McGill pain questionnaire(SF-MPQ)sensory score(P＜0.05),and the Ne of right rectus gyrus of the TN group was positively correlated with the disease duration(P＜0.05).Conclusion The TN group retain σ,but the overall information transfer efficiency of the brain is reduced and functional integration is diminished.Several brain regions in the TN group has abnormal Ne,which provide an objective basis for altered brain functional networks in TN.
