Clinical study of transcatheter drug-loaded microsphere embolization in the treatment of patients with advanced bladder cancer with bleeding
10.3969/j.issn.1002-1671.2024.10.028
- VernacularTitle:经导管载药微球栓塞术治疗晚期膀胱癌伴出血患者的临床研究
- Author:
Qihong CHEN
1
;
Qingxian ZHANG
;
Jianxiong LIN
;
Jinqi HUANG
;
Xiaojie GAO
Author Information
1. 莆田市第一医院介入血管外科,福建 莆田 351100
- Keywords:
transcatheter drug-loaded microsphere embolization;
bladder cancer;
bleeding
- From:
Journal of Practical Radiology
2024;40(10):1699-1701,1716
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility,safety and efficacy of transcatheter drug-loaded microsphere embolization(DLME)in treating patients with advanced bladder cancer with bleeding(ABCB).Methods A total of 26 ABCB patients who underwent DLME for tumor supply arteries were retrospectively selected.The postoperative efficacy and related complications were observed.The recurrence of hematuria and survival situation were followed up.Results All 26 surgeries achieved success with a technical success rate of 100.0％.There were 21 cases(80.8％)of bilateral bladder artery embolism and 5 cases(19.2％)of unilateral bladder artery embolism.Three days after the operation,24 patients(92.3％)had hematuria remission.And the other two patients(7.7％)had no hematuria remission,they were relieved after interventional embolization again.Compared with that before operation,the blood transfusion rate,blood transfusion volume,hematocrit and hemoglobin at one week after operation were significantly improved(P＜0.05).One month after the last intervention,there were 2 cases of complete response,19 cases of partial response,3 cases of stable disease,and 2 cases of progressive disease.The objective remission rate was 80.8％,and the disease control rate was 92.3％.Compared with that before operation,the T stage was significantly improved at one month after operation(P＜0.05).No patients had severe complications such as ectopic embolism.After follow-up for 3-36 months,5 cases(19.2％)had a recurrence of hematuria.Conclusion Transcatheter DLME is feasible,safe,and effective in the treatment of patients with ABCB.It is an optional,minimally invasive palliative measure.
