Correlation analysis between tibial plateau varus and osteoporosis in postmenopausal women with knee osteoarthritis
10.3969/j.issn.1002-1671.2024.10.023
- VernacularTitle:绝经后女性膝骨性关节炎患者胫骨平台内翻与骨质疏松的相关性分析
- Author:
Junlu ZHAO
1
;
Zhai LIU
;
Yiming GAO
;
Jingyu LI
;
Qingyun REN
Author Information
1. 河北医科大学第一医院放射科,河北 石家庄 050031
- Keywords:
osteoporosis;
knee osteoarthritis;
unicompartmental knee arthroplasty;
tibial plateau varus
- From:
Journal of Practical Radiology
2024;40(10):1674-1677
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between tibial plateau varus and osteoporosis(OP)in postmenopausal women with knee osteoarthritis(KOA).Methods A retrospective analysis was conducted on 194 postmenopausal women with KOA who underwent unicompartmental knee arthroplasty.Various risk factors associated with tibial plateau varus[medial tibial plateau angle(MTPA)＜85°],including age,body mass index(BMI),Kellgren-Lawrence(K-L)grade,hip-knee-ankle angle(HKAA),lateral distal femur angle(LDFA),bone mineral density(BMD)were collected and analyzed.Multiple regression was employed to analyze the relationship of these factors with tibial plateau varus.Pearson's correlation coefficient was used to assess the association between MTPA and BMD.Results Multiple linear regression analysis revealed that BMD(β=0.381,P＜0.001)and HKAA(β=0.460,P＜0.001)were independent risk factors for tibial plateau varus.LDFA,age,BMI,K-L grade were not significantly associated with tibial plateau varus.A statistically significant association between BMD and tibial plateau varus was noted(r=0.817,P＜0.001).Further data stratification showed a significant association between BMD and tibial plateau varus in patients with knee varus(HKAA＜175°)(r=0.781,P＜0.001).There was no statistical significance association between BMD and tibial plateau varus in patients with normal lower extremity alignment(HKAA≥175°)(r=-0.035,P=0.063).Conclusion OP and knee varus emerge as the primary risk factors for tibial plateau varus in the knee in postmenopausal women with KOA.
