The value of multiple imaging parameters based on CT derived fractional flow reserve and fat attenuation index in predicting major adverse cardiac events in patients with obstructive coronary heart disease
10.3969/j.issn.1002-1671.2024.10.011
- VernacularTitle:基于CT血流储备分数和脂肪衰减指数的多成像参数预测阻塞性冠心病患者主要不良心脏事件的价值
- Author:
Qiusi XING
1
,
2
;
Xiangsheng LI
;
Yuan FANG
;
Xiaoxia CHANG
;
Jingyao XU
Author Information
1. 河北北方学院,河北 张家口 075000
2. 空军军医大学空军特色医学中心医学影像科,北京 100142
- Keywords:
coronary heart disease;
major adverse cardiac events;
CT derived fractional flow reserve;
fat attenuation index
- From:
Journal of Practical Radiology
2024;40(10):1625-1629
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of CT derived fractional flow reserve(CT-FFR)combined with pericoronary adipose tissue(PCAT)fat attenuation index(FAI)in predicting major adverse cardiac events(MACE)in patients with obstructive coronary heart disease(CHD).Methods A total of 149 patients with obstructive CHD who underwent coronary computed tomography angiography(CCTA)examination were analyzed retrospectively.The patients were divided into MACE group and non-MACE group according to the occurrence of MACE.The clinical data,CCTA characteristics,CT-FFR,PCAT volume and FAI differences between the two groups were compared.Multiple logistic regression analysis was used to screen the independent predictors of MACE.The area under the curve(AUC)of the receiver operating characteristic(ROC)curve was used to evaluate the efficiency of a single independent predictor and its joint prediction of MACE.Results CT-FFR≤0.8 and right coronary artery(RCA)FAI(RCA-FAI)were independent risk factors for MACE in patients with obstructive CHD.The AUC of CT-FFR≤0.8 and RCA-FAI to predict MACE in patients with obstructive CHD were 0.773 and 0.766,respectively,while of their combination was 0.865.Conclusion Compared with single imaging parameters,the combined imaging parameters of CT-FFR and RCA-FAI can significantly improve the predictive efficiency of MACE in patients with obstructive CHD.
