Research advances in the role of CX3CL1 and its receptor in liver diseases
10.3760/cma.j.issn.1007-3418.2016.04.016
- VernacularTitle:趋化因子CX3CL1及其受体在肝脏疾病中的研究进展
- Author:
Pan ZHANG
1
;
Shengsong HE
;
Qiaoxia TONG
Author Information
1. 华中科技大学同济医学院附属协和医院感染科
- Keywords:
Carcinoma,hepatocellular;
Hepatitis;
Liver cirrhosis;
CX3CL1
- From:
Chinese Journal of Hepatology
2016;24(4):313-316
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,an increasing number of studies have found that the interaction between CX3CL1 and its receptor plays an important role in a series of inflammatory,infectious,and neurological processes and in various cancers.Therefore,its therapeutic targeting represents a promising treatment strategy for diseases.This review summarizes the structure,biological function,and mechanism of signal transduction of CX3CL1 and its receptor,and introduces the research progress in CX3CL1 and its receptor in hepatitis,hepatic fibrosis,cirrhosis,and hepatoma.
