The value of quantitative parameters of diffusion weighted imaging in differentiating the nature of ovarian epithelial tumors
10.3969/j.issn.1002-1671.2024.09.016
- VernacularTitle:扩散加权成像定量参数对鉴别卵巢上皮性肿瘤性质的价值
- Author:
Jiaojiao FAN
1
;
Yang LIU
;
Ruichao LIU
;
Guanxiong LI
;
Ziteng XIE
;
Wei XIA
Author Information
1. 保定市第一中心医院医学影像一科,河北 保定 071000
- Keywords:
ovarian epithelial tumor;
apparent diffusion coefficient;
logistic regression
- From:
Journal of Practical Radiology
2024;40(9):1468-1471,1498
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of minimum apparent diffusion coefficient(ADCmin)and delta apparent diffusion coefficient(dADC)of quantitative parameters of MR diffusion weighted imaging(DWI)in differentiating benign from stage Ⅰ malignant ovarian epithelial tumors.Methods A total of 112 patients with primary ovarian epithelial tumors confirmed by operation and pathology(43 benign tumors and 69 stage Ⅰ malignant tumors)were retrospectively selected.All patients underwent routine MRI and DWI before operation.The ADCmin and dADC of solid portion were measured and compared between the two groups.Logistic regression anal-ysis and receiver operating characteristic(ROC)curve were used to evaluate diagnostic performance of each parameter alone and in combination in differentiating ovarian epithelial benign and stage Ⅰ malignant tumors.Results The ADCmin was greater in benign tumors than that in stage Ⅰ malignant tumors,while dADC was smaller in benign tumors than that in stage Ⅰ malignant tumors(P＜0.05).Logis-tic regression analysis showed that ADCmin and dADC were independent risk factors for stage Ⅰ malignant tumors.With threshold of 1.183 × 10-3 mm2/s for ADCmin and 0.579 × 10-3 mm2/s for dADC,the area under the curve(AUC)was 0.802 and 0.857,sensitivity and specificity of 0.885,0.808,0.714,0.857,respectively.According to regression equation logit(P)=7.154+0.267 × dADC-1.016 X ADCmin,the AUC(0.951)was greater than that of single parameter,the sensitivity was 0.890,the specificity was 0.995.Conclusion ADCmin and dADC are useful for differentiating ovarian epithelial benign from stage Ⅰ malignant tumors,and ADCmin combined with dADC can improve the diagnose accuracy before operation.
