Sole percutaneous microwave coagulation versus its combination with transcatheter arterial chemoembolization for treatment of primary hepatoma: a comparison study
10.3760/cma.j.issn.1007-3418.2016.04.007
- VernacularTitle:单纯微波消融与其联合肝动脉化学栓塞治疗原发性肝癌的对比研究
- Author:
Yong ZENG
1
,
2
;
Yongsong GUAN
Author Information
1. 610041成都,四川大学华西医院
2. 611830都江堰,四川省都江堰市人民医院
- Keywords:
Carcinoma,hepatocellular;
Microwaves;
Ablation techniques;
Therapy;
Chemoembolization,therapeutic
- From:
Chinese Journal of Hepatology
2016;24(4):275-278
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and adverse effects of sole percutaneous microwave coagulation therapy (PMCT) compared to that of PMCT combining with transcatheter arterial chemoembolization (TACE) for the treatment of primary hepatoma.Methods A total of 50 patients diagnosed with primary hepatocellular carcinoma were recruited and divided into two groups.Group A included 15 patients only treated with PMCT.The other 35 ones falling into group B were treated with PMCT in combination with TACE.Analysis of therapeutic efficacy and adverse effects were conducted.Results The objective effect rates in group A and group B were 40.0% and 62.8%,respectively.There was no significant difference between the two groups(P =0.136).The one-year survival rates of the two groups were 46.6% and 71.4%,respectively(P =0.095);and the twoyear survival rates were 26.7% and 42.8%,respectively (P =0.048).No grade Ⅲ adverse effects or beyond were observed.Conclusion PCMT combining with TACE is safe and more effective in one-year survival than PCMT alone for the treatment of primary hepatocellular carcinoma.