Predictive value of dynamic contrast-enhanced MRI combined with molybdenum target mammography for postoperative recurrence of triple-negative breast cancer
10.3969/j.issn.1002-1671.2024.09.012
- VernacularTitle:动态对比增强MRI结合钼靶X线对三阴性乳腺癌术后复发的预测价值
- Author:
Wei WANG
1
;
Bowen WEI
;
Chuanle LI
;
Heshan HAN
Author Information
1. 阜阳市肿瘤医院医学影像科,安徽 阜阳 236000
- Keywords:
triple-negative breast cancer;
dynamic contrast-enhanced magnetic resonance imaging;
molybdenum target mammog-raphy;
recurrence
- From:
Journal of Practical Radiology
2024;40(9):1449-1452
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)combined with molybdenum target mammography for postoperative recurrence of triple-negative breast cancer(TNBC).Methods A total of 185 patients with TNBC radical surgery were selected,who all underwent DCE-MRI and molybdenum target mammography before surgery,and were followed up after surgery.The DCE-MRI results and molybdenum target mammography signs of the two groups were compared.The influencing factors of TNBC postoperative recurrence were analyzed.A prediction model was established and its prediction efficiency was evaluated.Results As of the follow-up time,the recurrence rate was 23.56％.Logistic risk regression model showed that percentage of type Ⅲ time-signal intensity curve(TIC),volume transfer constant(Ktrans),rate constant(Kep),and microcalcification nature were risk factors for TNBC postoperative recurrence(P＜0.05).The exponential equation was fitted,logit(P)=-9.187+0.215X1+0.962X2+1.145X3+0.733X4.The Hosmer-Lemeshow goodness-of-fit test results showed that the model had a high goodness-of-fit(x2=6.214,P=0.138).The area under the curve(AUC)of risk score prediction for postopera-tive recurrence was 0.908,while the sensitivity was 91.67％,and the specificity was 81.52％.Conclusion The risk prediction model based on DCE-MRI and molybdenum target mammography has a high predictive value for TNBC postoperative recurrence.
