Comparative analysis of imaging manifestations and pathology in congenital cystic adenomatoid malformation of the lung
10.3969/j.issn.1002-1671.2024.09.007
- VernacularTitle:先天性肺囊性腺瘤样畸形的影像表现与病理对照分析
- Author:
Zhenhua JIAO
1
;
Lianfeng LIU
;
Ting GAO
;
Fenjuan ZHANG
;
Yuanqing HE
;
Chenchen QIN
Author Information
1. 咸阳市中心医院 影像中心,陕西 咸阳 712000
- Keywords:
cystic adenomatoid malformation;
lung;
congenital;
computed tomography;
pathology
- From:
Journal of Practical Radiology
2024;40(9):1425-1428
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between the imaging manifestations and pathological classification of congeni-tal cystic adenomatoid malformation of the lung(CCAM).Methods A retrospective analysis was conducted on the clinical and radiologic data of nine patients with pathologically confirmed CCAM,and all data were compared with Stocker pathological classification,respec-tively.Results The CT images of all nine patients demonstrated cysts filled with either gas or fluid,which corresponded exactly with their gross pathological outcomes.Four cases of large cystic CCAM(cyst diameter exceeding 2 cm)were consistent with Stocker type Ⅰ.CT findings showed single or multiple capsular cavities occupying the thoracic cavity,with gas or fluid mainly in the cyst.Two cases exhibited mass effect and expansion of the involved lung lobes,while two cases showed localized decreased density around the lesion.The pathological features of these large cystic CCAM included single or multiple thick-walled cysts,with pseudostratified ciliated colum-nar epithelium lining the cyst lumen observed under microscopy.The other five cases of small cystic CCAM(cyst diameter less than 2 cm)matched Stocker type Ⅱ.CT findings showed multiple thin-walled cellular cysts confined to a single lung lobe,and none of these patients had significant mass effect or expansion of the involved lung lobes.Pathologically,these cases were characterized by multiple small cysts with septa,and the cysts were primarily lined with ciliated columnar or cuboidal epithelium upon microscopy.Conclusion CT imaging of CCAM has specific manifestations,with accurately displaying the distribution range and morphological characteristics of the lesions and reflecting the internal histological characteristics.There is a significant correlation between the CT manifestations of CCAM and their pathological classification.
