Analysis of the short-term efficacy and safety of percutaneous liver puncture in the local treatment of portal vein thrombosis
10.3969/j.issn.1002-1671.2024.08.027
- VernacularTitle:经皮肝穿刺局部处理门静脉血栓形成短期疗效与安全性分析
- Author:
Ting CUI
1
;
Tao WANG
;
Bing ZHU
;
Mingming MENG
;
Bowen LIU
;
Yifan LÜ
;
Quan CHEN
;
Yifan WU
;
Yu ZHANG
;
Chengbin DONG
;
Fuquan LIU
Author Information
1. 首都医科大学附属北京世纪坛医院介入治疗科,北京 100038
- Keywords:
venous thrombosis;
portal vein;
percutaneous liver puncture;
thrombolytic therapy
- From:
Journal of Practical Radiology
2024;40(8):1338-1341
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the short-term efficacy and safety of percutaneous liver puncture for local management of portal vein thrombosis(PVT).Methods Variations in thrombus,blood flow,and laboratory examination results were observed before and after percutaneous liver puncture in 197 patients with PVT,and the occurrence of comorbidities was recorded and followed up for one year after treatment.Results After treatment,the thrombus in the main portal vein vessels almostly disappeared in 119 patients(60.41％)with PVT,the thrombus had a significant reduction in 57 patients(28.93％),and the thrombus had a smaller change or an increase in 21 patients(10.66％);146 patients(74.11％)had smooth blood flow in the main portal vein vessels,29 patients(14.72％)showed significant improvement in blood flow,and 22 patients(11.17％)showed no significant improvement or worsening of blockage.The mean portal venous pressure was significantly lower than that before treatment(P＜0.001);thrombin time,activated partial thromboplastin time,and prothrombin time were prolonged compared to those before thrombolysis(P＜0.001),and fibrinogen were reduced compared to those before thrombolysis(P＜0.001).A total of 35 patients(17.77％)occured comorbidities during treatment.One year after treatment,196 patients(99.49％)with PVT survived,of which thrombus essentially disappeared in 141(71.94％),thrombus stabilized(or decreased)in 42(21.43％),and thrombus increased in 13(6.63％).Conclusion percutaneous liver puncture for local management of PVT is effective and reliable in the short-term and requires standardized management of the entire process.
