CT and MRI features of intraosseous myofibroma/myofibromatosis in children
10.3969/j.issn.1002-1671.2024.08.026
- VernacularTitle:儿童骨内肌纤维瘤/肌纤维瘤病的CT和MRI表现
- Author:
Lixin YANG
1
;
Xingfeng YAO
;
Xiaolu TANG
;
Rongchang WU
;
Yun PENG
Author Information
1. 首都医科大学附属北京儿童医院影像中心,北京 100045
- Keywords:
children;
myofibroma/myofibromatosis;
bone;
computed tomography;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2024;40(8):1334-1337
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the CT and MRI features of intraosseous myofibroma/myofibromatosis in pediatric patients.Methods The retrospective analysis involved the examination of clinical data and imaging findings from 15 children who were diagnosed with myofibroma/myofibromatosis of bone invasion through pathological means.Subsequently,the imaging characteristics were summarized.Results CT examinations were conducted on a total of 15 patients,with 2 of them also received enhanced scans.Additionally,MRI examinations were conducted on 5 patients,with 3 of them also underwent enhanced scans.Eleven patients were diagnosed with solitary type myofibroma,with 7 cases localized in the skull and the remaining lesions observed in the maxillofacial bone.Three patients exhibited the multicentric type without any involvement of visceral organs,while one patient presented with the multicentric type accompanied by visceral involvement.The lesions exhibited a uniform soft-tissue density on plain CT scan,predominantly located between the inner and outer layers of the bone.Additionally,they displayed swelling changes and osteolytic bone destruction,with some lesions showed residual bone shell.On MRI,the lesions exhibited a uniform signal,demonstrated an isointense or slightly hypointense signal on T1WI and an isointense or slightly hyperintense signal on T2WI.The lesions displayed significantly heterogeneous enhancement on CT and MRI.Conclusion The imaging manifestations of intraosseous myofibroma/myofibromatosis in pediatric patients exhibit certain characteristics,and the residual bone shell in the lesion is helpful for diagnosis,however,distinguishing it from Langerhans cell histiocytosis of the bone remains challenging,necessitating the reliance on pathological diagnosis.