HCV infection and specific T lymphocyte immunity
10.3760/cma.j.issn.1007-3418.2016.03.003
- VernacularTitle:HCV感染与特异性T淋巴细胞免疫
- Author:
Jijing SHI
1
;
Jiyuan ZHANG
;
Xuexiu ZHANG
;
Fusheng WANG
Author Information
1. 100039,北京大学解放军302医院教学医院感染性疾病诊疗与研究中心
- Keywords:
T-lymphocytes;
Immunity;
Hepatitis C virus
- From:
Chinese Journal of Hepatology
2016;24(3):170-174
- CountryChina
- Language:Chinese
-
Abstract:
Adaptive immunity,especially the cellular immunity mediated by T lymphocytes,plays an important role in the body's fight against hepatitis C virus (HCV) infection.The clearance of HCV requires a strong,sustained,and multi-epitope response from specific T lymphocytes,and the dysfunction of specific T lymphocytes is the major reason for chronic infection.Effective treatment can restore the function of specific T lymphocytes to a certain extent.This article reviews the features and related mechanisms of immune response from specific T lymphocytes when the prognosis of patients with HCV infection is different.
