Evaluation of Crohn's disease treatment efficacy with CT enterography
10.3969/j.issn.1002-1671.2024.08.018
- VernacularTitle:CT小肠造影对克罗恩病疗效评估的价值
- Author:
Fang WEN
1
;
Fuxia XIAO
;
Kun PENG
;
Yali XU
;
Guangyu TANG
;
Yi FEI
Author Information
1. 上海市第十人民医院放射科,上海 200072
- Keywords:
Crohn's disease;
treatment efficacy;
computed tomography
- From:
Journal of Practical Radiology
2024;40(8):1300-1303
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of CT enterography(CTE)in the clinical treatment efficacy evaluation of Crohn's disease(CD).Methods A total of 55 patients with CD confirmed by clinical and pathology were selected.All patients both underwent CTE and enteroscopy before and after treatment.After treatment,the patients were divided into the good curative effect group and the poor curative effect group according to Crohn's disease activity index(CDAI).The CT findings were both analyzed before and after treatment.Results There were significant differences in bowel wall thickness,bowel wall attenuation,bowel wall thickness type and"comb sign"of 55 CD patients before and after treatment(P＜0.05).After treatment,phlegmon,abscess,swollen lymph node enlargement,and intestinal fistula all decreased from 18％,7％,27％,and 2％to 2％,2％,9％,and 0％,respectively.Also,there were significant differences in bowel wall thickness,bowel wall attenuation,bowel wall thickness type and"comb sign"between the good curative effect group and the poor curative effect group(P＜0.05).Logistic regression analysis and receiver operating characteristic(ROC)curve analysis showed bowel wall thickness,bowel wall attenuation and bowel wall thickness type were the most valuable parameters for the treatment efficacy evaluation of CD patients.Conclusion CTE can fully show intestinal lesions and extrenteral complications,and is of great value in evaluating clinical treatment efficacy of patients.
