Application value of intravoxel incoherent motion and dynamic contrast-enhanced MRI in prognostic staging evaluation of early-stage rectal adenocarcinoma
10.3969/j.issn.1002-1671.2024.08.016
- VernacularTitle:体素内不相干运动及动态对比增强MRI在早期直肠腺癌预后分期评估中的应用价值
- Author:
Yaxin CHAI
1
;
Yongchao NIU
;
Dan SONG
Author Information
1. 新乡市中心医院MR室 新乡医学院第四临床学院,河南 新乡 453500
- Keywords:
rectal adenocarcinoma;
intravoxel incoherent motion;
dynamic contrast-enhanced magnetic resonance imaging;
prog-nostic stage
- From:
Journal of Practical Radiology
2024;40(8):1291-1295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the application value and diagnostic efficiency of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)and intravoxel incoherent motion(IVIM)in prognostic staging of early-stage rectal adenocarcinoma.Methods Eighty-one patients with early-stage rectal adenocarcinoma confirmed by surgery were retrospectively selected.They were examined by high-resolution MRI,IVIM and DCE-DWI before operation.According to prognostic staging criteria,they were divided into stageⅠ and stage Ⅱ A groups.The quantitative parameters of DCE-MRI and IVIM were obtained by GenIQ or MITK software respectively.The differences of parameter values between the two groups were compared by independent sample t-test or Mann-Whitney U test,and the diagnostic efficiency was analyzed.Results The values of rate constant(Kep),volume transfer constant(Ktrans)and pseudo diffusion coefficient(D*)in stage Ⅰ group were lower than stage Ⅱ A group(P＜0.05).The f value in stage Ⅰ group was higher than stage Ⅱ A group(P＜0.05).D*and Kep values were included in the binary logistic regression equation.The receiver operating characteristic(ROC)curves of D*,Kep values and their joint prediction probability values were obtained,and the area under the curve(AUC)were 0.791,0.770 and 0.852 respectively.The sensitivities were 90.91％,66.67％and 81.82％respectively.The specificities were 66.67％,83.33％and 79.17％respectively.Conclusion D*and Kep values have the potential to be imaging indicators of prognostic staging of early-stage rectal adenocarcinoma,and to guide the selection of clinical treatment schemes.
