Analysis of the clinical,pathological and CT features of mediastinal carcinoid
10.3969/j.issn.1002-1671.2024.08.009
- VernacularTitle:纵隔类癌的临床特征、病理及CT表现分析
- Author:
Mingjing CHEN
1
;
Ling HE
;
Qian LI
;
Yongmei YU
;
Zhongchun ZHOU
Author Information
1. 济宁市第一人民医院放射科,山东 济宁 272000
- Keywords:
mediastinum;
carcinoid;
computed tomography
- From:
Journal of Practical Radiology
2024;40(8):1259-1262
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical,pathological and CT features of mediastinal carcinoid so as to improve the diagnostic accuracy.Methods The clinical,pathological and imaging data of 4 patients with mediastinal carcinoid were analyzed retrospectively.Results All 4 patients were elderly male,in which 3 cases had elevated serum neuron specific enolase(NSE)before operation and other one was not examined.All tumors were atypical carcinoid with Ki-67 expression of 5％-25％and positive expression of Syn,CD56,CK and CgA.The CT showed the lateral mass on the left(n=3)or both(n=1)sides of the anterior mediastinum,3 of which grew along the vascular space and could not be clearly demarcated from the pericardium and cardiovascular system.The lesions were large with irregular shape in 3 cases and round shape in 1 case,with heterogeneous density in 3 cases and homogeneous density in 1 case,with intratumoral calcification in 2 cases.Contrast enhanced CT showed the lesions with mild or moderate progressive enhancement,3 of which had supplying vessels from internal thoracic artery.The enlarged mediastinal lymph nodes were found in 3 cases and bone metastasis was in 1 case.Conclusion Mediastinal carcinoid is more common in elderly male,usually with elevated serum NSE.CT shows lateral mass in the anterior mediastinum with heterogeneous density,intratumoral calcification,mild or moderate progressive enhancement,and supplying vessels from internal thoracic artery.The larger lesion is indistinguishable from the adjacent lung tissue and cardiovascular system,usually with intrathoracic and extrathoracic lymph node metastasis.
