MR study based on ASL and IVIM in the ipsilateral thalamic diaschisis after unilateral supratentorial cerebral infarction
10.3969/j.issn.1002-1671.2024.08.001
- VernacularTitle:单侧幕上脑梗死后同侧丘脑神经机能联系不能的MR IVIM和ASL研究
- Author:
Na TIAN
1
,
2
;
Qinghua ZHANG
;
Lei ZHAO
;
Yun YUE
;
Chengxin YAN
Author Information
1. 山东第一医科大学第二附属医院影像科,山东 泰安 271000
2. 南京中医药大学连云港附属医院放射科,江苏 连云港 222004
- Keywords:
ipsilateral thalamic diaschisis;
cerebral infarction;
magnetic resonance imaging;
intravoxel incoherent motion;
arterial spin labeling
- From:
Journal of Practical Radiology
2024;40(8):1219-1223
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of intravoxel incoherent motion(IVIM)parameters in the diagnosis of ipsilateral thalamic diaschisis(ITD)after unilateral supratentorial cerebral infarction via combination of arterial spin labeling(ASL)and IVIM.Methods A total of 111 patients with cerebral infarction were selected,including 61 patients in the acute stage(＞6 h-3 d),50 patients in the subacute stage(＞3 d-11 d).All patients were subjected to MRI examination,and the diffusion weighted imaging(DWI),ASL,and IVIM image data were uploaded to the GE workstation.The regions of interest(ROI)in the bilateral thalamus were selected,and the cerebral blood flow(CBF),D*,D,and f values were measured,and the asymmetry index(AI)was calculated.ITD was diagnosed according to AI＞10％,and all patients were divided into ITD-positive and ITD-negative groups.The differences of each parameter between the two groups and their relationship with AI were analyzed.Results In acute stage and subacute stage cerebral infarction,the CBF,D*and D values of ipsilateral thalamus were lower than those of contralateral thalamus,while the f value was higher than those of contralateral thalamus.There was no statistical significance in D*,D and f values between ITD-positive and ITD-negative groups after acute stage cerebral infarction(P＞0.05).There were significant differences in CBF,apparent diffusion coefficient(ADC),D and f values in ITD-positive group after subacute stage cerebral infarction(P＜0.05),but no significant differences in D*value of ITD-positive group and CBF,D*,D,f values of ITD-negative group(P＞0.05).AI-D*,AI-D and AI-ADC in subacute stage were positively correlated with AI-CBF,while AI-f was negatively correlated with AI-CBF.The area under the curve(AUC)of AI-D and AI-f in subacute stage were 0.749 and 0.699,respectively.Conclusion The combination of ASL and IVIM has confirmed the phenomenon of ITD after unilateral supratentorial cerebral infarction,with high diagnostic efficacy of quantitative parameters D value and f value.It can non-invasively evaluate the thalamic microstructural and perfusion changes in the early stage after cerebral infarction.
