Application of oral Gadovist in three-dimensional sampling perfection with application optimized contrasts using different flip angle evolutions MR cholangiopancreatography
10.3969/j.issn.1002-1671.2024.06.032
- VernacularTitle:口服钆布醇在三维可变反转角快速自旋回波MR胰胆管成像中的应用
- Author:
Zidong ZHANG
1
;
Peicai CAO
;
Hongquan ZHAO
;
Yufei CHEN
Author Information
1. 烟台业达医院影像科,山东 烟台 264006
- Keywords:
Gadovist;
three-dimensional sampling perfection with application optimized contrasts using different flip angle evolu-tions;
magnetic resonance cholangiopancreatography;
image quality;
concentration
- From:
Journal of Practical Radiology
2024;40(6):998-1001
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the appropriate concentration of oral Gadovist solution for improving the image quality of three-dimensional sampling perfection with application optimized contrasts using different flip angle evolutions magnetic resonance cholangiopancreatography(3D-SPACE-MRCP).Methods In vitro experiments,0.05％,0.1％,0.15％and 0.2％Gadovist solution and direct drinking water were put into 100 mL plastic containers respectively for 3D-SPACE-MRCP scanning to measure the signal intensity(SI)of Gadovist solutions in each group.The concentration and the SI of Gadovist solution were analyzed with Spearman correlation,and one-way variance analysis was performed to compare the SI of different concentration Gadovist solutions.In clinical experiments,128 subjects were randomly divided into 4 groups,and then taken orally 300 mL of 0.05％,0.1％,0.15％and 0.2％Gadovist solutions respectively.The 3D-SPACE-MRCP scanning was performed,and the image quality was evaluated by two physicians and compared by one-way variance analysis.Results In vitro experiments,there was an extremely strong negative correlation between the concentration and the SI of Gadovist solution(r=-0.969,P＜0.05),and there were significant differences in the SI among different concentrations of Gadovist solution(P＜0.05).In clinical experiments,among the 26 cases with first-level images,24 cases were distributed in the 0.1％Gadovist solution group.There was a statistically significant difference in image quality of the 3D-SPACE-MRCP with different oral concentrations of Gadovist solution(F=89.57,P＜0.05),however,there was no statistically significant difference between the 0.15％and the 0.2％Gadovist solution groups using the Tukey test(P＞0.05).Conclusion Oral Gadovist solution can significantly improve the images quality of 3D-SPACE-MRCP,and 0.1％solution is the appropriate dilution concentration.
