Prediction of lung hemorrhage after microwave ablation in stage ⅠA non-small cell lung cancer patients
10.3969/j.issn.1002-1671.2024.06.026
- VernacularTitle:ⅠA期非小细胞肺癌患者微波消融术后肺出血的预测
- Author:
Jingshuo LI
1
;
Shengmei MA
;
Haipeng JIA
;
Yuxian CHEN
;
Chunhai LI
Author Information
1. 山东大学齐鲁医院放射科,山东 济南 250012
- Keywords:
non-small cell lung cancer;
lung hemorrhage;
microwave ablation;
computed tomography
- From:
Journal of Practical Radiology
2024;40(6):973-976
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop an nomogram model for predicting the lung hemorrhage after CT-guided microwave ablation(MWA)in stage ⅠA non-small cell lung cancer(NSCLC)patients.Methods Stage ⅠA NSCLC patients treated with MWA were randomly divided into a training group and a validation group in a 3∶1 ratio.The risk factors of lung hemorrhage identified by univariable and multivariable logistic regression analysis in the training group were used to develop a nomogram model.The C-statistic was used to evaluate the predictive accuracy in both the training and validation groups.Results A total of 208 patients(training group,156 cases;validation group,52 cases)were included in this study.The risk factors of lung hemorrhage after MWA were the number of vessels passing through the lung parenchyma[odds ratio(OR)=3.815;95％confidence interval(CI)1.485-9.800;P=0.005],number of focal blood supplies(OR=2.922;95％CI 1.198-7.126;P=0.018)and number of punctures(OR=2.802;95％CI 1.792-4.381;P＜0.001).The C-statistic in training group was 0.928(95％CI 0.875-0.963)and the C-statistic in validation group was 0.906(95％CI 0.793-0.969).The optimal cut-off value for lung hemorrhage was 0.14.Conclusion The nomogram model can effectively predict the lung hemorrhage after MWA.Patients showing a high risk(＞0.14)on the nomogram model should be monitored for lung hemorrhage.
