Correlation between coronary heart disease and osteoporosis based on coronary CT angiography
10.3969/j.issn.1002-1671.2024.06.010
- VernacularTitle:基于冠状动脉CT血管成像的冠心病与骨质疏松的相关性研究
- Author:
Xuewen LIU
1
;
Shikui SHI
Author Information
1. 蚌埠医学院第一附属医院放射科,安徽 蚌埠 233000
- Keywords:
coronary heart disease;
osteoporosis;
coronary computed tomography angiography
- From:
Journal of Practical Radiology
2024;40(6):903-906,935
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between coronary heart disease(CHD)and osteoporosis(OP)based on coronary computed tomography angiography(CTA).Methods Data of patients with coronary CT A were prospectively collected.A total of 130 patients with CHD were included in the experimental group,and 61 patients without CHD were included in the control group matched by age and gender.General information and blood biochemical indexes of patients were collected.Coronary CTA data was transmitted to Shukun Technology software to obtain coronary assessment indicators;Bone mineral density(BMD)of the T9-T11 was measured using quantitative computed tomography(QCT)software.The correlation between CHD and OP was analyzed with the obtained data.Results BMD in the experimental group was lower than that in the control group(P＜0.01),and the fat attenuation index(FAI)was higher than that in the control group(P＜0.001).BMD in the experimental group was highly negatively correlated with calcification score(r,=-0.35,P=0.001);The BMD of the extremely low risk group was higher than that of the other three groups(P＜0.01);The degree of coronary stenosis was lower in the extremely low and low risk groups than in the other two groups(P＜0.001).BMD in the experimental group was highly negatively correlated with the degree of coronary stenosis(r=-0.29,P＜0.001);The FAI in the occlusion group was the highest.There was no correlation between BMD and FAI in the experimental group;The degree of coronary stenosis and calcification score in FAI＞-70 HU group were higher than FAI≤-70 HU group(P＜0.01).Conclusion CHD is closely related to OP.Coronary plaque calcification accelerates bone loss and aggravates coronary stenosis.When the calcification score is more than 100,the effect on coronary stenosis and bone loss is more significant.
