Longitudinal study on cancer-related fatigue among breast cancer patients during comprehensive treatment period
10.3760/cma.j.issn.1674-2907.2017.04.006
- VernacularTitle:综合治疗期乳腺癌患者癌因性疲乏的纵向研究
- Author:
Meifang WANG
1
;
Wanxia YAO
Author Information
1. 710018,西安交通大学城市学院
- Keywords:
Breast neoplasms;
Cancer-related fatigue;
Longitudinal studies
- From:
Chinese Journal of Modern Nursing
2017;23(4):466-470
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the level of cancer-related fatigue (CRF) and its trajectory in three different periods including operation,chemotherapy,and radiotherapy among breast cancer patients,in order to provide references for clinical intervention during comprehensive treatment period.Methods By convenience sampling method,242 cases of patients diagnosed with breast cancer who are prepared for breast cancer resection,prepared to be treated with adjuvant chemotherapy and radiotherapy,and conformed to the sample standard from a tumor hospital and two affiliated hospitals of medical college from February 2014 to November 2015 in a city were selected as the research object. The follow-up survey of CRF was conducted respectively in the three different point-in-time for one week after operation,and at the end of chemotherapy and radiotherapy in order to analyze variation characteristics of CRF during comprehensive treatment period.Results In operation period,the fatigue of breast cancer patients was mild,the average scores was (2.59±2.41) and approximately 76% patients experienced fatigue to low-grade degree;After chemotherapy,the fatigue level of patients was significantly increased (6.57±2.43),and 75.2% patients were accounted for severe fatigue;After radiotherapy, the fatigue level of patients (4.38±2.46) was slightly declined compared with that in chemotherapy period,but it was still higher than that in the operation period. and 57% patients suffered from moderate fatigue. During the whole treatment period,the level for general fatigue and four dimensions of fatigue were in the unstable state of "wave" of fluctuations with mild,severe,moderate (F=43.16,P<0.001).Conclusions There is a certain difference with CRF of breast cancer patients at different stage of comprehensive treatment. CRF in operation period is mild,in radiotherapy period is moderate and in chemotherapy period is severe. We should actively focus on the changes of CRF in order to take timely intervention.
