CT manifestations and clinical features of thymic lymphoepithelioma-like carcinoma in children and literature review

VernacularTitle:儿童胸腺淋巴上皮瘤样癌的CT表现及临床特征并文献复习
Author: Lixin YANG ¹ ; Di HU ; Zhonglong HAN ; Shuangfeng YANG ; Yun PENG
Author Information

1. 首都医科大学附属北京儿童医院影像中心,北京 100045
Keywords: children; thymus; lymphoepithelioma-like carcinoma; computed tomography
From: Journal of Practical Radiology 2024;40(5):789-792
CountryChina
Language:Chinese
Abstract: Objective To investigate the CT manifestations and clinical features of thymic lymphoepithelioma-like carcinoma(LELC)in children.Methods The CT findings and clinical features of 5 children with LELC confirmed by pathology were analyzed retrospectively,and relevant literatures were reviewed.Results All the five children showed a large soft tissue mass(a few punctuate calcifications in 3 cases)in the anterior and middle mediastinum,which was lobulated.After enhancement,the tumor showed signifi-cant heterogeneous enhancement with cystic,necrosis,compressing,surrounding and invading adjacent structures.Twenty-one children with LELC were searched in literatures.Conclusion Thymic LELC in children usually occurs in adolescent boys aged 10-16 years.Those children usually go to the doctor with symptoms of tumor compression or invasion of adjacent structures.LELC shows advanced clinical stage with poor prognosis.CT enhancement can accurately display the lesion and invasion of adjacent structures,and guide clinical staging and treatment.