Application of multimodal MRI in the efficacy evaluation of intraocular retinoblastoma
10.3969/j.issn.1002-1671.2024.05.024
- VernacularTitle:多模态MRI在眼内期视网膜母细胞瘤疗效评估中的应用
- Author:
Lin LI
1
;
Zhiqun SUN
;
Fangyuan LI
Author Information
1. 山东大学附属儿童医院医学影像中心,山东 济南 250022
- Keywords:
multimodal magnetic resonance imaging;
intraocular period;
retinoblastoma;
efficacy evaluation
- From:
Journal of Practical Radiology
2024;40(5):785-788
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of multimodal MRI in evaluating the efficacy of retinoblastoma(RB)after selective ophthalmic artery infusion(SOAI)in children.Methods The MRI and clinical data of 80 children with intraocular RB with monocu-lar disease after chemotherapy were collected.The changes of MRI parameters in children with successful and failed eye protection before and after chemotherapy was analyzed.Results After chemotherapy,the maximum tumor diameter and △ SI were significantly reduced,the distance between tumor and optic disc and apparent diffusion coefficient(ADC)were significantly increased,the calcifi-cation/tumor ratio was increased,and the change of eyeball size was not obvious in the children with successful eye protection com-pared with before treatment.After chemotherapy,the maximum tumor diameter and the range of retinal detachment were significantly increased,and the cross-sectional area of the eyeball was significantly reduced,and △ SI,ADC and calcification/tumor ratio were not significantly changed compared with before treatment in the children with failed eye protection.Conclusion Multimodal MRI can accu-rately evaluate the effectiveness of chemotherapy in children and provide conclusive evidence for the formulation of subsequent treat-ment plans.
