Correlation between digital mammography features,LMR level and clinical prognosis in patient with invasive breast cancer
10.3969/j.issn.1002-1671.2024.05.011
- VernacularTitle:数字化乳腺钼靶特征、LMR水平与浸润性乳腺癌临床预后的相关性研究
- Author:
Guangmei LI
1
;
Shuihong CHEN
;
Xiaoli LOU
;
Haidong CUI
Author Information
1. 永康市妇幼保健院放射科,浙江 永康 321300
- Keywords:
invasive breast cancer;
digital mammography;
lymphocyte to monocyte ratio;
prognosis
- From:
Journal of Practical Radiology
2024;40(5):729-732
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation between digital mammography features,lymphocyte to monocyte ratio(LMR)and prognosis in patient with invasive breast cancer,and to explore the prognostic value of digital mammography features and LMR in invasive breast cancer.Methods Ninety-six patients with invasive breast cancer were selected.The data of digital mammography features and serum LMR levels were analyzed.The patients were followed up after discharge.According to different prognosis,all patients were divided into good prognosis group(68 cases)and poor prognosis group(28 cases).Spearman was used to analyze the correlation of digital mammography features,LMR level and prognosis of patients.Receiver operating characteristic(ROC)curve was drawn to analyze the prognostic value of digital mammography features and LMR level.Results The spicule sign and proportion of calcifica-tion in the poor prognosis group was significantly higher than that in the good prognosis group,the maximum diameter of tumor was significantly larger than that in the good prognosis group,and the serum LMR level was significantly lower than that in the good prognosis group(P＜0.05).Spearman correlation analysis showed that spicule sign,proportion of calcification and maximum diame-ter of tumor were positively correlated with poor prognosis of invasive breast cancer(P＜0.05).Serum LMR level was negatively correlated with poor prognosis of invasive breast cancer(P＜0.05).ROC curve analysis showed that the area under the curve(AUC)of spicule sign,calcification and tumor maximum diameter combined with LMR level to evaluate the prognosis of invasive breast cancer was 0.927,the sensitivity was 89.71％,and the specificity was 82.14％,which were significantly higher than those of each index alone.Conclusion Digital mammography and serum LMR levels may be closely related to the prognosis of patients with invasive breast cancer,and spicule sign,calcification,tumor maximum diameter combined with serum LMR may be of significant prognostic value in invasive breast cancer.
